Buy 4-FMC Flephedrone Online. The amount of research data on 4-FMC is comparatively small in comparison with other cathinones such as 4-methyl-N-methylcathinone (mephedrone) or 3,4-methylenedioxypyrolvalerone (MDPV) but the currently available data suggest that the psychoactive and behavioural profile of 4-FMC, for example demonstrated by drug
discrimination and in-vitro studies, show similarities to psychomotor stimulants such as cocaine, methcathinone and methamphetamine although it appears that it be less potent. It has been demonstrated that key targets of 4-FMC include monoamine transporters and that it functions as a catecholamine-selective substrate-type releaser of dopamine and
While 4-FMC was a low potency partial agonist at the 5-HT1A receptor, it was found to be an antagonist with very low potency at 5-HT2A and 5-HT2C receptors. Buy 4-FMC Flephedrone Online. 4-FMC was observed to act primarily as a substrate at the human dopamine (hDAT) and human norepinephrine transporter (hNET), with the latter being more pronounced than methamphetamine. In addition, it was observed to display appreciable affinity to the hα1A adrenoceptor and rat trace amine-associated receptor 1.
The ability to induce DA release similar to methamphetamine-type substances known to act as hDAT substrates makes it likely that 4-FMC may show abuse potential. It seems conceivable that, especially at high dosage levels, extensive release of NE in combination with hα1A adrenoceptor activation might also contribute to enhanced cardiotoxic effects, in addition to